Users Online: 855
Home Print this page Email this page
Home About us Editorial board Search Browse articles Submit article Ahead of Print Instructions Subscribe Contacts Special issues Login 
RESEARCH ARTICLE
Year : 2021  |  Volume : 10  |  Issue : 1  |  Page : 38

Diagnostic accuracy of magnetic resonance cholangiopancreatography to detect benign and malignant biliary strictures


Department of Radiology, Isfahan University of Medical Sciences, Isfahan, Iran

Correspondence Address:
Dr. Shadi Ebrahimian
Department of Radiology, Isfahan University of Medical Sciences, Hezar Jerib Avenue, Isfahan
Iran
Login to access the Email id

Source of Support: The study was supported by Isfahan University of Medical Sciences, Conflict of Interest: None


DOI: 10.4103/abr.abr_137_20

Rights and Permissions

Background: Magnetic resonance cholangiopancreatography (MRCP) is a noninvasive method to detect pancreaticobiliary strictures. In this study, we aimed to evaluate the diagnostic performance of MRCP and detect sensitive and specific radiologic features in distinguishing malignant and benign pathologies. Materials and Methods: In this study, 50 patients with biliary obstruction and a confirmed diagnosis using histopathology were included. The pathologies were evaluated using MRCP which were categorized into malignant and benign strictures. The etiology of strictures was detected using histopathology and endoscopic retrograde cholangiopancreatography. The diagnostic performance of MRCP was calculated using SPSS software. P < 0.05 was considered statistically significant. Results: Of 50 patients, 23 patients (46%) had malignant strictures based on MRCP and histopathology. The sensitivity and specificity of MRCP to detect malignancy were 95.7% and 96.3%, respectively. The most sensitive MRCP features to detect malignancy were upstream biliary duct dilation, abrupt tapering, and the presence of a solid mass with sensitivity 100%, 95.7%, and 78.2%, respectively. The malignancy rate was significantly higher in the strictures with length >11.5 mm or wall thickness >2.75 mm (P < 0.05). Conclusion: MRCP is a sensitive method to differentiate malignant lesions from benign pathologies. A long and thick stricture with the presence of a solid mass, upstream biliary duct dilation, and abrupt tapering is highly suggestive of malignancy.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1842    
    Printed50    
    Emailed0    
    PDF Downloaded361    
    Comments [Add]    

Recommend this journal