| ORIGINAL ARTICLE |
|
| Year : 2023 | Volume
: 12
| Issue : 1 | Page : 140 |
|
|
Evaluation of the incidence of the esophagogastric pre-cancerous mucosal lesions after bariatric surgery
Behrooz Keleidari1, Hamid Melali1, Mohsen Mahmoudieh Dehkordi1, Masoud Sayadi1, Fatemeh Allahbakhshian Farsani2, Mohammad Fakhrolmobasheri3, Mahmood Mostafavi1
1 Department of General and Laparoscopic Surgery, Isfahan University of Medical Sciences, Isfahan, Iran
2 Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran
3 Heart Failure Research Institute, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Correspondence Address:
Dr. Mahmood Mostafavi
Fellowship in Minimally Invasive and Laparoscopic Surgery, Department of General and Laparoscopic Surgery, Isfahan University of Medical Sciences, Isfahan
Iran
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/abr.abr_148_22
|
|
|
Background: Bariatric surgery is associated with significant risk reduction for obesity-related and hormone-mediated cancers; however, few studies report gastric or esophageal cancer development after bariatric surgery. This study evaluates the incidence of pre-cancerous mucosal lesions one year after bariatric surgery.
Materials and Methods: Eligible patients for omega-loop gastric bypass and classic Roux-en-Y gastric bypass (RYGB) underwent upper endoscopy before bariatric surgery and one year after the procedure. Several biopsies were obtained from esophagogastric mucosa, all of which were evaluated by pathologists regarding the development of any pre-cancerous lesion.
Results: A total of 108 patients were included in the study. Seventy-one underwent omega bypass and 37 classic RYGB. Follow-up endoscopy indicated no dysplastic changes in esophagogastric mucosa one year after the surgery. The number of patients with gastric intestinal metaplasia was 22 and 25 before and after the surgery, respectively, which was not a statistically significant increase.
Conclusion: Bariatric surgeries might not increase the risk of developing pre-cancerous lesions in the esophagogastric mucosa. Further epidemiological studies may help to establish this finding.
|
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
