| SYSTEMATIC REVIEW |
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| Year : 2023 | Volume
: 12
| Issue : 1 | Page : 147 |
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Diagnosis and treatment of coagulopathy caused by the new coronavirus: A systematic review and meta-analysis protocol
Sadegh Abbasian1, Mahya Razmi2, Hadiseh Bahramian3, Mostafa Shanbehzadeh4, Hadi Kazemi-Arpanahi5
1 Department of Laboratory Science, School of Paramedical Sciences, Ilam University of Medical Sciences; Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran
2 Student Research Committee, Faculty of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran
3 Student Research Committee, Faculty of Paramedical Sciences, Lorestan University of Medical Sciences, Khorramabad, Iran
4 Department of Health Information Technology, School of Allied Medical Sciences, Ilam University of Medical Sciences, Ilam, Iran
5 Department of Health Information Technology, Abadan University of Medical Sciences; Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran
Correspondence Address:
Dr. Hadi Kazemi-Arpanahi
Department of Health Information Technology, Abadan University of Medical Sciences, Abadan 6313833177
Iran
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/abr.abr_403_21
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Background: The new coronavirus is an agent of respiratory infections associated with thrombosis in vital organs. This study aimed to propose a better diagnosis and treatment of coagulation disorders caused by the new coronavirus (Covid-19).
Materials and Methods: Search in Cochrane central, Web of Science, PubMed, Scopus, and Ovid will be done. Also, according to the inclusion criteria, cross-sectional studies, cohort, clinical trial, and case-control will be included without gender and language restriction. Participants will also be Covid-19 patients with coagulation disorders. Any disagreement in the stages of screening, selection, and extraction of data between the two reviewers will be resolved by discussion, then if not resolved, the opinion of expert reviewers will be used. The risk of bias will be assessed using the NOS (Newcastle–Ottawa scale) tool for cross-sectional study, cohort and case-control, and the Cochrane checklist for clinical trials study. Metaanalysis of included studies that are similar based on the methodology will be done. Also, a fixed or random-effect model will be used for this it. Heterogeneity indices (I2), odds ratio (OR), risk ratio (RR), mean difference, and %95 confidence interval will also be calculated by Stata V.13.0 (Corporation, College Station TX).
Results: Treatment with anticoagulants will reduce the severity of thrombosis and lung disease in patients. D-dimer measurement will also be a diagnosis indicator of thrombosis.
Conclusions: Simultaneous study of coagulation disorders and thrombosis in patients and development of a Godliness based on it will play a treatment role in the follow-up of the coronavirus disease.
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