| REVIEW ARTICLE |
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| Year : 2023 | Volume
: 12
| Issue : 1 | Page : 159 |
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Association of lymphovascular space invasion (LVSI) with histological tumor grade and myometrial invasion in endometrial carcinoma: A review study
Azita Rafiee1, Fereshteh Mohammadizadeh2
1 Pathologist, Iranian Medical and Pathology Laboratory, Zahedan, Iran
2 Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Correspondence Address:
Dr. Azita Rafiee
Pathologist, Iranian Medical and Pathology Laboratory, Zahedan
Iran
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/abr.abr_52_23
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Endometrial carcinoma is one of the most frequent gynecological cancers in developed countries. Lymphovascular space invasion (LVSI), histological grade, and myometrial invasion (MMI) are important prognostic factors of endometrial carcinoma. LVSI is considered an independent poor prognostic factor in endometrial carcinoma. Based on the importance of LVSI, this study aimed to discuss the association of LVSI with tumor grade and MMI. A search of PubMed, EMBASE, Web of Science, Scopus, Google Scholar, and Cochrane Library was carried out to collect related studies. Consequently, most studies showed that LVSI is significantly associated with higher histologic grade and deep MMI.
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