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Case Report:
Cellular Therapy for Chronic Traumatic Brachial Plexus Injury
Alok Sharma, Hemangi Sane, Nandini Gokulchandran, Prerna Badhe, Suhasini Pai, Pooja Kulkarni, Jayanti Yadav, Sanket Inamdar
Adv Biomed Res
2018, 7:51 (27 March 2018)
DOI
:10.4103/2277-9175.228631
PMID
:29657936
Cellular therapy is being actively pursued as a therapeutic modality in many of the neurological diseases. A variety of stem cells from diverse sources have been studied in detail and have been shown to exhibit angiogenetic and immunomodulatory properties in addition to other neuroprotective effects. Published clinical data have shown bone marrow mononuclear cell (BMMNC) injection in neurological disorders is safe and possesses regenerative potential. We illustrate a case of 27-year-old male with traumatic brachial plexus injury, administered with autologous BMMNCs intrathecally and intramuscularly, followed by multidisciplinary rehabilitation. At the follow-up assessment of 3 and 7 months after first cell transplantation, improvements were recorded in muscle strength and movements. Electromyography (EMG) performed after the intervention showed a response in biceps and deltoid muscles suggesting the process of reinnervation at the site of injury. In view of the improvements observed after the treatment, the patient underwent second cell transplantation 8 months after the first transplantation. Muscle wasting had completely stopped with an increase in the muscle girth. No adverse effects were noted. Improvements were maintained for 4 years. A comprehensive randomized study for this type of injury is needed to establish the therapeutic benefits of cellular therapy.
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Case Report:
A Large Primary Subcutaneous Hydatid Cyst in Proximal Thigh: An Unusual Localization
Farzaneh Hekmatnia, Mehdi Motififard, Hossein Ahrar Yazdi, Abdellah Maleki Rizi, Pegah Hedayat, Ali Hekmatnia
Adv Biomed Res
2018, 7:50 (27 March 2018)
DOI
:10.4103/2277-9175.228622
PMID
:29657935
Primary muscular hydatidosis is a very rare condition with an incidence of 1%–4% in endemic regions. This case report describes an unusual location of hydatid cyst in the sartorius muscle and the application of imaging in its preoperative diagnosis, choosing a treatment strategy, and monitoring.
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Month wise articles
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2023
February
[
2
]
January
[
2
]
2022
December
[
2
]
November
[
1
]
October
[
3
]
August
[
1
]
April
[
2
]
January
[
3
]
2021
December
[
1
]
November
[
1
]
October
[
1
]
September
[
2
]
2020
December
[
1
]
November
[
2
]
September
[
2
]
August
[
4
]
July
[
1
]
June
[
1
]
2019
November
[
1
]
September
[
2
]
May
[
1
]
March
[
1
]
January
[
1
]
2018
December
[
1
]
November
[
1
]
September
[
1
]
July
[
1
]
June
[
2
]
May
[
4
]
April
[
1
]
March
[
2
]
February
[
1
]
January
[
1
]
2017
December
[
2
]
October
[
1
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August
[
1
]
July
[
2
]
June
[
1
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May
[
1
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March
[
2
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February
[
1
]
2016
December
[
3
]
September
[
1
]
August
[
1
]
April
[
2
]
March
[
4
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January
[
1
]
2015
August
[
4
]
July
[
1
]
May
[
1
]
March
[
2
]
February
[
5
]
January
[
3
]
2014
December
[
4
]
November
[
3
]
September
[
2
]
August
[
1
]
July
[
1
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June
[
2
]
March
[
2
]
February
[
1
]
January
[
11
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2013
November
[
1
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July
[
2
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June
[
1
]
March
[
9
]
2012
October
[
2
]
August
[
3
]
July
[
3
]
May
[
3
]
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Online since 15 January, 2012