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  Indian J Med Microbiol
 

Figure 2: Quantitative real-time PCR analysis of expression of TLR-2, 7, 8 in human PBMC. (a) Relative mRNA expression of TLR-2 in UC patients compared with healthy individuals. (b) Significant upregulation of TLR-7 in UC patients compared with healthy individuals. (c) Relative mRNA expression of TLR-8 in UC cases compared with healthy groups. (d) Relative mRNA expression of TLR-2 at flareup and remission clinical course of ulcerative colitis. (e) A significant increment in relative mRNA expression of TLR-7 at remission course of the disease. (f) Relative mRNA expression of TLR-8 at the active and inactive course of UC. Student t-test and One-way ANNOVA analysis were applied. TLR-2, Toll-like receptor-2; TLR-7, Toll-like receptor-7; TLR-8, Toll-like receptor-8; UC, ulcerative colitis; (*P < 0.05) (**P < 0.01) (***P < 0.001)

Figure 2: Quantitative real-time PCR analysis of expression of TLR-2, 7, 8 in human PBMC. (a) Relative mRNA expression of <i>TLR-2</i> in UC patients compared with healthy individuals. (b) Significant upregulation of <i>TLR-7</i> in UC patients compared with healthy individuals. (c) Relative mRNA expression of <i>TLR-8</i> in UC cases compared with healthy groups. (d) Relative mRNA expression of <i>TLR-2</i> at flareup and remission clinical course of ulcerative colitis. (e) A significant increment in relative mRNA expression of <i>TLR-7</i> at remission course of the disease. (f) Relative mRNA expression of <i>TLR-8</i> at the active and inactive course of UC. Student <i>t</i>-test and One-way ANNOVA analysis were applied. TLR-2, Toll-like receptor-2; TLR-7, Toll-like receptor-7; TLR-8, Toll-like receptor-8; UC, ulcerative colitis; (*<i>P</i> < 0.05) (**<i>P</i> < 0.01) (***<i>P</i> < 0.001)